2019年4月26日14:57:43饮食健康防止氟化物破坏大脑的香料已关闭评论2.1K19字数 6990阅读23分18秒阅读模式



Fluoride is found everywhere today,from antibiotics to drinking water,no stick pans to toothpaste,making exposure inevitable.All the more reason why research proving this common spice can prevent fluoride damage is so promising...


Fluoride's neurotoxicity has been the subject of academic debate for decades,and now a matter of increasingly impassioned controversy among the general public,as well.From'conspiracy theories'about it being first used in drinking water in Russian and Nazi concentration camps to chemically lobotomize captives,to its now well-knownIQ lowering properties,to its ability to enhance the calcification of the pineal gland–the traditional'seat of the soul'–many around the world,and increasingly in the heavilyfluoridated regions of the United States,are starting to organize at the local and statewide level to oust this ubiquitous toxicant from municipal drinking water.


A compelling study published in the Pharmacognosy Magazine titled,"Curcumin attenuates neurotoxicity induced by fluoride:An in vivo evidence,"adds experimental support to the suspicion that fluoride is indeed a brain-damaging substance,also revealing that a natural spice-derived protective agent against the various health effects associated with this compound is available.


The study was authored by researchers from the Department of Zoology,University College of Science,M.L.Sukhadia University,Udaipur,India,who have spent the past decade investigating the mechanisms through which fluoride induces severe neurodegenerative changes in the mammalian brain,particularly in cells of the hippocampus and cerebral cortex.[[i]] [[ii]]


The study opens by describing the historical backdrop for concern about fluoride's significant and wide ranging toxicity:


"Fluoride(F)is probably the first inorganic ion which drew attention of the scientific world for its toxic effects and now the F toxicity through drinking water is well-recognized as a global problem.Health effect reports on F exposure also include various cancers,adverse reproductive activities,cardiovascular,and neurological diseases.[1,2]"

"氟化物(F)可能是第一个因其毒性效应而引起科学界注意的无机离子,现在通过饮用水产生的 f 毒性已被公认为一个全球性问题。有关氟暴露的健康影响报告还包括各种癌症、不良生殖活动、心血管和神经系统疾病。[1,2]

The study focused on fluoride induced neurotoxicity,identifying excitoxicity(stimulation of the neuron to the point of death)and oxidative stress as the two main drivers of neurodegeneration.It has been observed that subjects with the condition known as fluorosis,a mottling of tooth enamel caused by excessive exposure to fluoride during tooth development,also have neurodegenerative changes associated with a form of oxidative stress known as lipid peroxidation(rancidity).Excess lipid peroxidation in the brain can lead to a decrease in total brain phospholipid content.Owing to these well-known mechanisms of fluoride associated neurotoxicity and neurodegeneration,the researchers identified the primary polyphenol in the spice turmeric--known as curcumin–as an ideal agent worth testing as a neuroprotective substance.Previous research on curcumin indicates that it is capable of activing as an antioxidant in 3 distinct ways by protecting against:1)singlet oxygen 2)hyrodxyl radicals and 3)superoxide radical damage.Also,curcumin appears to raise endogenous glutathione production in the brain,a major antioxidant defense system.



2)hyrodxyl 自由基和


In order to assess the neurotoxic effects of fluoride and prove curcumin's protective role against it,researchers randomly divided up mice into four groups,for 30 days:


1.Control(no fluoride)


2.Fluoride(120 ppm):fluoride was given in distilled water drinking water without restriction.


3.Fluoride(120 ppm/30 mg/kg body weight)+Curcumin:Oral dose of curcumin dissolved in olive oil along with fluoride in drinking water

氟化物(120ppm/30mg/kg 体重)+姜黄素:口服剂量姜黄素溶解在橄榄油和氟化物在饮用水

4.Curcumin:(30 mg/kg body weight)


In order to ascertain the effect of treatment,the researchers measured the malondialdehyde(MDA)content in the brains of the different treated mice.MDA is a well-known marker of oxidative stress/damage.


As was expected,the fluoride(F)only treatment group showed significantly elevated MDA levels vs.the non-fluoride treated control.The F+Curcumin group saw reduced MDA levels vs.the fluoride only group,demonstrating curcumin's neuroprotective activity against fluoride associated neurotoxicity.

正如预期的那样,仅氟化物(F)治疗组与未氟化物处理的对照组相比,MDA 水平显著升高。与单纯氟化物组相比,F+姜黄素组的 MDA 水平降低,表明姜黄素对氟化物相关的神经毒性具有神经保护作用。

The study concluded,


"Our study thus demonstrate that daily single dose of 120 ppm F result in highly significant increases in the LPO[lipid peroxidation,i.e.brain rancidity]as well as neurodegenerative changes in neuron cell bodies of selected hippocampal regions.Supplementation with curcumin significantly reduce the toxic effect of F to near normal level by augmenting the antioxidant defense through its scavenging property and provide an evidence of having therapeutic role against oxidative stress mediated neurodegeneration."

"因此,我们的研究表明,每天单剂量120ppm D 会导致 LPO[脂质过氧化酸败]高度显著增加,以及特定海马区神经元细胞体的神经退行性变化。补充姜黄素可以通过其清除能力增强抗氧化防御功能,从而显著降低 f 的毒性作用至接近正常水平,并提供了对氧化应激介导的神经退行性疾病有治疗作用的证据



This is far from the first study to demonstrate curcumin's remarkable brain-saving properties.From the perspective of the primary research alone,there are over two hundred peer-reviewed published studies indicating that curcumin is a neuroprotective agent.On our own turmeric database we have 115 articles proving this statement:Turmeric Protects The Brain.We have also featured studies on turmeric's ability to protect and restore the brain:


   How Turmeric Can Save the Aging Brain From Dementia and Premature Death


   Turmeric Produces'Remarkable'Recovery in Alzheimer's Patients


Considering the many chemical insults we face on a daily basis in the post-industrial world,turmeric may very well be the world's most important herb,with over 800 evidence-based health applications.Visit our Turmeric Research database--the world's largest,open access turmeric resource of its kind--to view the first hand published research on the topi.


For more information,please review the following content:


   The Turmeric Drink that Can Revolutionize Your Health


    Research:Curcumin Is A Triple Negative Breast Killer


   Science Confirms Turmeric As Effective As 14 Drugs





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